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 The secondary alcohol cyclododecanol (CDOL) is a colorless solid with a pronounced camphor-like odor. It is readily soluble in organic solvents but has only limited solubility (0.004% by weight) in water.
CDOL is produced by boric-acid catalyzed oxidation of cyclododecane.
- CDOL is an intermediate in the synthesis of laurolactam, the monomer of polyamide 12 (VESTAMID® L). Laurolactam itself is synthesized from cyclododecane, with cyclododecanol, cyclododecanone and cyclododecanone oxime as intermediates in successive steps.
- oxidative ring cleavage of CDOL gives 1,12-dodecanedioic acid, also an important component for polymer synthesis.
- the fragrance industry uses CDOL to a large extent for synthesis of macrocyclic perfume ingredients with a musky note.
- fragrances of a woody character are also produced using CDOL.
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